The use of High Flow Nasal Cannula during care manoeuvres in patients (hospitalized adults) with SARS-CoV-2 infection: retrospective cohort study.

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Valentina Baldi
Giorgio Bergesio
Sandro Longu
Massimiliano Brando

Abstract

INTRODUCTION


14% of patients with SARS-cov-2 infection progress to hypoxia respiratory failure requiring oxygen therapy. The objective of the study is to assess the effectiveness and safety of high-flow nasal oxygen (HFNC) during assistive maneuvers (personal hygiene, self-care and nutrition) in patients with SARS-cov-2 infection.


MATERIALS AND METHODS


With a retrospective cohort study design with a statistical analysis of inferential type, in three subintensive departments of the Local Health Authority of Asti from 8 November 2020 to 20 January 2021, the documentation of patients from 41 to 100 years old with SARS-cov-2 infection who used HFNCs during assistive maneuvers alternating with the CPAP helmet/mask was examined. For the research of the sample was used the program Dshop®, in which the ages, the percentages of FiO2 and the cmh2o of PEEP administered to the patients were collected and ventilation parameters were detected.


RESULTS


Analysis of 536 medical records 114 were included in the study. There was a significant reduction in po2 and po2/FiO2 ratio and a decrease in spo2 in the oldest age group in the sample [91-100] when using HFNC. With regard to FiO2, a significant reduction in spo2 and P/F was shown with the administration of FiO2 by 90-100%. Finally, with the HFNC the values of HCO3 and lactates are contained in the optimal values of the EGA unlike the helmet/ mask CPAP with PEEP of 15 cmh2o.


DISCUSSION AND CONCLUSIONS


The HFNC is associated with increased comfort in fact the patient can hydrate, feed, perform hygiene and self-care independently. The CPAP ventilatory mode, on the other hand, requires a strong human-device collaboration, the patients often turn out to be anxious, claustrophobic and not adherent.

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How to Cite
Baldi, V., Bergesio, G., Longu, S., & Brando, M. (2022). The use of High Flow Nasal Cannula during care manoeuvres in patients (hospitalized adults) with SARS-CoV-2 infection: retrospective cohort study. Journal of Biomedical Practitioners, 6(1). https://doi.org/10.13135/2532-7925/6837
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References

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